MATLAB PROJECT
Live Ultrasound
Color-Encoded Speckle Imaging Platform for Real-Time Complex Flow Visualization
In Vivo
Abstract:
Complex flow patterns are prevalent in the
vasculature, but they are difficult to image noninvasively in real time. This
paper presents the first real-time scanning platform for a high-frame-rate
ultrasound technique called color-encoded speckle imaging (CESI) and its use in
visualizing arterial flow dynamics in vivo. CESI works by simultaneously
rendering flow speckles and color-coded flow velocity estimates on a
time-resolved basis. Its live implementation was achieved by integrating a
192-channel programmable ultrasound front-end module, a 4.8-GB/s capacity data
streaming link, and a series of computing kernels implemented on the graphical
processing unit (GPU) for beamforming and Doppler processing. A slow-motion
replay mode was also included to offer coherent visualization of CESI frames
acquired at high frame rate [3000 frames per second (fps) in our experiments].
The live CESI scanning platform was found to be effective in facilitating
real-time image guidance (at least 20 fps for live video display with 55-fps
GPU processing throughout). In vivo pilot trials also showed that live CESI,
when running in replay mode, can temporally resolve triphasic flow at the
brachial bifurcation and can reveal flow dynamics in the brachial vein during a
fist-clenching maneuver. Overall, live CESI has potential for use in routine
investigations in vivo that seek to identify complex flow dynamics in real time
and relate these dynamics to vascular physiology.
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